PR-39 TFA

CAT: 0931-MF-0155588-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0155588-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Proteasome|||Antibacterial
Related Pathways
Proteases/Proteasome|||Ubiquitination|||Microbiology/Virology
Bioactivity
PR-39 TFA, a natural peptide rich in proline and arginine with antibacterial properties, acts as a noncompetitive, reversible, and allosteric inhibitor of the proteasome. It specifically attaches to the ?7 subunit of the proteasome, preventing the degradation of the NF-?B inhibitor I?B? through the ubiquitin-proteasome pathway. Additionally, PR-39 TFA promotes angiogenesis, suppresses inflammatory responses, and notably decreases myocardial infarct size in mice [1] [2].
Molecular Formula
C231H347F3N70O42
Molecular Weight
4833.76
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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