PR-39 TFA

• Target :

  Proteasome|||Antibacterial

• Related Pathways :

  Proteases/Proteasome|||Ubiquitination|||Microbiology/Virology

• Bioactivity :

  PR-39 TFA, a natural peptide rich in proline and arginine with antibacterial properties, acts as a noncompetitive, reversible, and allosteric inhibitor of the proteasome. It specifically attaches to the ?7 subunit of the proteasome, preventing the degradation of the NF-?B inhibitor I?B? through the ubiquitin-proteasome pathway. Additionally, PR-39 TFA promotes angiogenesis, suppresses inflammatory responses, and notably decreases myocardial infarct size in mice [1] [2].

• Molecular Formula :

  C231H347F3N70O42

• Molecular Weight :

  4833.76

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C