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DCDAPH

CAT: 0931-T75378-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T75378-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
125113-96-4
Target
Beta Amyloid, Others
Related Pathways
Neuroscience, Others
Bioactivity
DCDAPH (Compound 2c), a novel smart near-infrared fluorescence (NIRF) probe, efficiently detects β-amyloid (Aβ) plaques with an excitation/emission wavelength (λ ex /λ em) of 597/665 nm in PBS. It demonstrates high affinity for Aβ aggregates, exhibiting a dissociation constant (Kd) of 27 nM and an inhibition constant (Ki) of 37 nM. Furthermore, DCDAPH exhibits favorable blood-brain barrier permeability, qualifying it as a suitable agent for both in vitro and in vivo detection of Aβ plaques [1].
Smiles
C(=CC=CC=C(C#N)C#N)C1=CC=C(N(C)C)C=C1
Molecular Formula
C16H15N3
Molecular Weight
249.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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#80030DCDAPH
81-2003DCDAPH Amyloid Stain

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