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Metrifonate

CAT: 0931-T75310-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T75310-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
52-68-6
Target
Parasite, Cholinesterase (ChE)
Related Pathways
Microbiology/Virology, Neuroscience
Bioactivity
Metrifonate is an organophosphorus prodrug that is metabolised non-enzymatically in the body to DDVP (dichlorvos), which acts as an irreversible cholinesterase (ChE) inhibitor. It inactivates ChE by phosphorylating the serine residue at its active site, making it useful for treating Alzheimer's disease and as an insecticide. Metrifonate affects AChE activity, oxidative stress, neurotoxicity, and cortisol levels in carp.
Smiles
O=P(OC)(OC)C(O)C(Cl)(Cl)Cl
Molecular Formula
C4H8Cl3O4P
Molecular Weight
257.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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