Products for Research Use Only
RegisterLogin

HBChE-IN-1

CAT: 0931-T74812-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T74812-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1776948-12-9
Target
Others, Microtubule Associated, Cholinesterase (ChE), Beta Amyloid
Related Pathways
Cytoskeletal Signaling, Others, Neuroscience
Bioactivity
HBChE-IN-1 (compound 4), a quinolizidinyl derivative, effectively inhibits human Butyrylcholinesterase (hBChE) with an IC50 value of 7 nM, demonstrating high selectivity against human Acetylcholinesterase (hAChE) . It also inhibits tau and Aβ 40 protein aggregation, with IC50 values of 20 and 4.3 μM, respectively, making it valuable for Alzheimer's disease research [1].
Smiles
N(CCCSC[C@H]1[C@@]2(N(CCC1)CCCC2)[H])C3=C4C(SC=5C(C4=O)=CC=CC5)=C(C)C=C3
Molecular Formula
C27H34N2OS2
Molecular Weight
466.7
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T200454-01HBChE-IN-3
T77509-01HBChE-IN-2
T5790-011,1,1,1-Kestohexaose
T83125-01AMPK-α1β1γ1 activator 1
T404761,1,1-Tribromoacetone
T78868-01TWIK-1/TREK-1-IN-1
T391821-Bromo-1,1-dichloroacetone
T391621,1,1,3-Tetrachloroacetone
T73743-011,1′,1′′,1′′′-[1,4-Piperazinediylbis (2,1-ethanediylnitrilo) ]tetrakis[2-dodecanol]
T211817-01C22:1 1-Deoxyceramide (m18:1/22:1)

Alternative Products

CatalogName
HY-149273HBChE-IN-1
HY-149993-01HBChE-IN-2
HY-169162HBChE-IN-3
OF59775-011,1,1,1,1-Kestoheptaose
N2864-5.11,1,1,1-Kestohexaose
1120401,1,1,1-Kestohexose

Popular Products