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THK01

CAT: 0931-T74808-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74808-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2226941-26-8
Target
ROCK, Others
Related Pathways
Stem Cells, Cell Cycle/Checkpoint, Others, Cytoskeletal Signaling
Bioactivity
THK01, a potent ROCK2 inhibitor, exhibits IC50 values of 5.7 nM for ROCK2 and 923 nM for ROCK1, respectively. It effectively targets the ROCK2-STAT3 signaling pathway to inhibit breast cancer metastasis, making it valuable for breast cancer research [1].
Smiles
O=C1C2=C3C(=C4C(=C2CN1)C=5C(N4)=CC=CC5)NC=6C3=CC(O)=CC6
Molecular Formula
C20H13N3O2
Molecular Weight
327.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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