HAA-09

• Target:

  Virus Protease|||Influenza Virus|||Others

• Related Pathways:

  Others|||Microbiology/Virology

• Bioactivity:

  HAA-09, an orally administered compound, serves as a powerful anti-influenza agent by targeting the influenza PB2_cap binding domain. It possesses significant activity against influenza A virus, exhibiting an EC50 of 0.03 ?M, and demonstrates polymerase inhibition with an IC50 of 0.06±0.004 ?M. Importantly, HAA-09 inhibits virus replication efficiently without inducing noticeable cytotoxicity [1].

• Smiles:

  FC=1C=C2C(=CNC2=NC1)C=3NC(=NN(CC(O)=O)C(C)(C)C)C(F)=CN3

• Molecular Formula:

  C17H18F2N6O2

• Molecular Weight:

  376.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1422051-33-9