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Eplontersen

CAT: 0931-T74645-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T74645-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1637600-16-8
Target
Others
Related Pathways
Others
Bioactivity
Eplontersen, a triantennary N-acetyl galactosamine (GalNAc3-7a) -conjugated antisense oligonucleotide, targets transthyretin (TTR) mRNA to suppress the synthesis of both variant and wild-type TTR proteins. The accumulation of misfolded TTR proteins contributes to the formation of amyloid fibrils in the heart and peripheral nerves, resulting in amyloid TTR (ATTR) amyloidosis [1] [2] [3].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C