RegisterLogin

SJ1008030

CAT: 0931-T74580-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T74580-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
2863634-96-0
Target
Others|||JAK|||PROTACs
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||PROTAC|||JAK/STAT signaling|||Stem Cells|||Others|||Chromatin/Epigenetic
Bioactivity
SJ1008030 (compound 8), a JAK2 PROTAC, selectively degrades JAK2. It demonstrates potent activity against MHH–CALL-4 cells, with an EC50 of 5.4 nM and an IC50 of 32.09 nM. This compound holds potential for leukemia research [1].
Smiles
CCS(=O)(=O)N1CC(CC#N)(C1)n1cc(cn1)-c1nc(Nc2ccc(cc2)C(=O)NCCN2CCN(CC2)c2ccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3c2)nc2[nH]ccc12
Molecular Formula
C42H43N13O7S
Molecular Weight
873.94
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T201713-01SJ1008066

Alternative Products

CatalogName
MBS5816526SJ1008030
OR1102042-01SJ1008030 formate
MBS5819615SJ1008030 formic
MBS5819614SJ1008030 TFA
HY-147330B-01SJ1008030 (formic)
HY-147330A-01SJ1008030 (TFA)
A24097-10SJ1008030 TFA 10mg
A23978-10SJ1008030 formic 10mg
A24097-1SJ1008030 TFA 1mg
A23978-1SJ1008030 formic 1mg

Popular Products