HD-TAC7

• CAS Number :

  2978763-95-8

• Target :

  PROTACs|||HDAC

• Related Pathways :

  DNA Damage/DNA Repair|||PROTAC|||Chromatin/Epigenetic

• Bioactivity :

  HD-TAC7, a potent PROTAC HDAC degrader, exhibits IC50 values of 3.6 ?M, 4.2 ?M, and 1.1 ?M for HDAC1, HDAC2, and HDAC3, respectively. It effectively decreases NF-?B p65 in RAW 264.7 macrophages and is utilized in research targeting inflammatory diseases such as asthma and chronic obstructive pulmonary disease (COPD) [1].

• Smiles :

  O=C(NC1=CC=C(F)C=C1N)C2=CC=C(C=C2)NC(=O)CCCCNC(=O)CNC3=CC=CC=4C(=O)N(C(=O)C34)C5C(=O)NC(=O)CC5

• Molecular Formula :

  C33H32FN7O7

• Molecular Weight :

  657.65

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C