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FAP-PI3KI1

CAT: 0931-T74402-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74402-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2415941-98-7
Target
Others, PI3K
Related Pathways
Others, PI3K/Akt/mTOR signaling
Bioactivity
FAP-PI3KI1, a fibroblast-activated protein (FAP) -targeted PI3K inhibitor, selectively targets FAP-expressing human idiopathic pulmonary fibrosis (IPF) cells. It effectively inhibits collagen synthesis and reduces collagen deposition [1].
Smiles
COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nccc(-c3ccc(COC(=O)OCCSSC[C@H](NC(=O)CCC(=O)NCc4cc(ccn4)C(=O)N[C@@H](C)C(=O)N4CC(F)(F)C[C@H]4C#N)C(O)=O)nc3)c2c1
Molecular Formula
C52H48F4N10O12S3
Molecular Weight
1177.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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