MS5033

CAT: 0931-T74299-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T74299-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2376137-29-8

Target

Others, Akt, PROTACs

Related Pathways

PI3K/Akt/mTOR signaling, Cytoskeletal Signaling, PROTAC, Others

Bioactivity

MS5033 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades AKT (also known as protein kinase B), exhibiting a half-maximal degradation concentration (DC50) of 430 nM in PC3 cells [1].

Smiles

NC1(CCN(CC1)c1ncnc2[nH]ccc12)C(=O)N[C@@H](CCN1CCN(CC1)C(=O)CCOCCOCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12)c1ccc(Cl)cc1

Molecular Formula

C51H66ClN11O11

Molecular Weight

1044.59

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Alternative Products

Catalog	Name
HY-143882	MS5033

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