DETQ

CAT: 0931-T73823-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T73823-01Size:5 mg
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CAS Number
1638667-81-8
Target
Dopamine Receptor|||Others
Related Pathways
Neuroscience|||GPCR/G Protein|||Others
Bioactivity
DETQ, a selective, allosteric, and orally active potentiator of the dopamine D1 receptor (Dopamine Receptor), enhances cAMP production in HEK293 cells expressing the human D1 receptor, achieving an EC50 of 5.8 nM and a K b of 26 nM. It demonstrates approximately 30-fold reduced potency at rat and mouse D1 receptors and shows no activity at the human D5 receptor [1].
Smiles
C[C@@H]1N([C@@H](CO)Cc2c1cccc2C(C)(C)O)C(=O)Cc1c(Cl)cccc1Cl
Molecular Formula
C22H25Cl2NO3
Molecular Weight
422.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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