(R) -Lanicemine

• Target:

  IGluR|||Others

• Related Pathways:

  Others|||Neuroscience|||Membrane transporter/Ion channel

• Bioactivity:

  (R) -Lanicemine ((R) -AZD6765), the less active R-enantiomer of Lanicemine, is a low-trapping NMDA channel blocker. It exhibits a binding affinity (Ki) of 0.56-2.1 ?M for the NMDA receptor and shows inhibitory concentrations (IC50s) of 4-7 ?M and 6.4 ?M in CHO and Xenopus oocyte cells, respectively. It has been associated with antidepressant effects [1].

• Smiles:

  N[C@H](Cc1ccccn1)c1ccccc1

• Molecular Formula:

  C13H14N2

• Molecular Weight:

  198.26

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  190581-71-6