Bufrolin

CAT: 0931-T73665-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T73665-01Size:5 mg
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CAS Number
54867-56-0
Target
Histamine Receptor|||GPCR|||Others
Related Pathways
Immunology/Inflammation|||Others|||GPCR/G Protein|||Neuroscience|||Endocrinology/Hormones
Bioactivity
Bufrolin, an analog of Cromoglycate (histamine release inhibitor) and a potent agonist of GPR35, enhances the interaction between ?-arrestin-2 and both human GPR35a and rat GPR35. It stabilizes mast cells, exhibiting antiallergic properties, and inhibits anti-inflammatory responses triggered by internalization peptides. Furthermore, Bufrolin is researched for its anti-inflammatory properties in pharmaceutic applications associated with internalization peptides [1] [2] [3].
Smiles
CCCCc1cc2c([nH]c(cc2=O)C(O)=O)c2c1[nH]c(cc2=O)C(O)=O
Molecular Formula
C18H16N2O6
Molecular Weight
356.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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