ZC0109

CAT: 0931-T73512-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T73512-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Target

Others, Apoptosis, Indoleamine 2,3-Dioxygenase (IDO), IDO

Related Pathways

Metabolism, Apoptosis, Others

Bioactivity

ZC0109, a dual inhibitor targeting IDO1 and Thioredoxin Reductase 1 (TrxR1) with IC50 values of 50 nM and 3.0 μM respectively, effectively promotes ROS accumulation and arrests the cell cycle at the G1/S phase, culminating in apoptosis of cancer cells.

Smiles

O=C(CC1=CC=C(O)C=C1)NC1=NN=C(CCCNC2=NON=C2/C(=N/O)NC2=CC(Br)=C(F)C=C2)S1

Molecular Formula

C22H20BrFN8O4S

Molecular Weight

591.41

Shipping Conditions

Ice Packs

Storage Temperature

-20°C