Erasin

CAT: 0931-T73472Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-T73472Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
STAT|||Apoptosis
Related Pathways
Stem Cells|||JAK/STAT signaling|||Apoptosis
Bioactivity
Erasin is a STAT3 inhibitor (IC50 = 9.7 ?M) with higher selectivity for inhibiting STAT3 tyrosine phosphorylation than STAT5 and STAT1. It induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and is effective against Erlotinib-resistant cancer cells.
Smiles
CC(C)(C)C1=CC(C2=O)=C(C=C1)OC=C2/C=N/NC(C3=CC=CN=C3)=O
Molecular Formula
C20H19N3O3
Molecular Weight
349.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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