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Erasin

CAT: 0931-T73472Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T73472Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
STAT, Apoptosis
Related Pathways
Stem Cells, JAK/STAT signaling, Apoptosis
Bioactivity
Erasin is a STAT3 inhibitor (IC50 = 9.7 μM) with higher selectivity for inhibiting STAT3 tyrosine phosphorylation than STAT5 and STAT1. It induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and is effective against Erlotinib-resistant cancer cells.
Smiles
CC(C)(C)C1=CC(C2=O)=C(C=C1)OC=C2/C=N/NC(C3=CC=CN=C3)=O
Molecular Formula
C20H19N3O3
Molecular Weight
349.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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HY-115594-01Erasin
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sc-144920-PRErasin (m) -PR
sc-144920Erasin siRNA (m)
sc-94539-PRErasin (h) -PR
sc-144920-SHErasin shRNA Plasmid (m)
sc-411689-HDRerasin HDR Plasmid (h)
sc-120085Erasin (m) : 293T Lysate
sc-426754-HDRerasin HDR Plasmid (m)
sc-94539-SHErasin shRNA Plasmid (h)

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