Products for Research Use Only

SG2057

CAT: 0931-T73469-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T73469-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
260417-62-7
Target
DNA Alkylator/Crosslinker, ADC Cytotoxin
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
SG2057 (DRG16), a potent antitumor agent, is a pyrrolobenzodiazepine (PBD) dimer connected by a pentyldioxy linkage. This compound selectively binds to the minor groove of DNA, forming both interstrand and intrastrand cross-linked adducts, contributing to its high antitumor activity.
Smiles
O=C1C=2C(=CC(OCCCCCOC3=C(OC)C=C4C(=C3)N=C[C@]5(N(C4=O)CC(=C)C5)[H])=C(OC)C2)N=C[C@]6(N1CC(=C)C6)[H]
Molecular Formula
C33H36N4O6
Molecular Weight
584.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C