Products for Research Use Only

BTK-IN-22

CAT: 0931-T73275-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73275-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2573048-10-7
Target
Others, BTK
Related Pathways
Angiogenesis, Others, Tyrosine Kinase/Adaptors
Bioactivity
BTK-IN-22, a BTK inhibitor (IC 50: 0.9 nM), also exhibits inhibition against BLX and BMX with IC 50 values of 1.4 and 1.2 nM, respectively. Demonstrating enhanced kinase selectivity, BTK-IN-22 outperforms Ibrutinib in this regard [1].
Smiles
NC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=C(C)C=C(OC5=CC=CC=C5)C=C4
Molecular Formula
C26H26N6O2
Molecular Weight
454.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C