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Fulzerasib

CAT: 0931-T73190-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T73190-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2641747-54-6
Target
Kras, Ras
Related Pathways
MAPK, GPCR/G Protein
Purity
0.9804
Bioactivity
Fulzerasib is an orally active KRAS G12C inhibitor that covalently binds to the cysteine residue on the protein, thereby inhibiting the growth of KRAS G12C mutant tumour cell lines, with an IC50 of 2–20 nM, and can be used to treat KRAS G12C mutant non-small cell lung cancer (NSCLC) .
Smiles
O=C(C=C)N1CCN2C=3C=4C=C(Cl)C(=NC4N(C(=O)C3N(C(=O)C2C1)C)C=5C(=NC=CC5C)C(C)C)C=6C(F)=CC=CC6O
Molecular Formula
C32H30ClFN6O4
Molecular Weight
617.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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