PTP1B-IN-20

CAT: 0931-T73072-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T73072-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Others, Phosphatase

Related Pathways

Others, Metabolism

Bioactivity

PTP1B-IN-20 is a selective PTP1B (protein tyrosine phosphatase 1B) inhibitor with an IC50 of 1.05 μM, demonstrating selectivity over TCPTP (T-cell protein tyrosine phosphatase) with an IC50 of 78.0 μM. It targets a crucial enzyme for inhibiting type 2 diabetes, showing preferential action on PTP1B over TCPTP.

Smiles

CC1=C(C=C2C(=C1O)C(=O)C3=C(C2=O)C(=C(C=C3)O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO[C@H]5[C@@H]([C@H]([C@@H](CO5)O)O)O)O)O)O

Molecular Formula

C26H28O15

Molecular Weight

580.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-N10648	PTP1B-IN-20
MBS8534661-01	PTP1B
QY-E05410	Human PTP1B (PTP1B) ELISA Kit
BAL2229	Phospho-PTP1B (Ser352) Rabbit mAb, 1 pack = 20 µL
BAL2310	Phospho-PTP1B (Ser378) Rabbit mAb, 1 pack = 20 µL
513271	PTP1B (PTP 1B, PTP1B, PTPN1) discontinued
BA8143-25	PTP1B-IN-22
BA8105-5.1	PTP1B-IN-1
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PTP1B-IN-20

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