PF-06455943

• Target:

  Others|||LRRK2

• Related Pathways:

  Autophagy|||Others

• Bioactivity:

  PF-06455943, a leucine rich repeat kinase 2 (LRRK2) inhibitor, exhibits an inhibition concentration (IC50) value of 3 nM and also functions as a PET radioligand. It is utilized in the research of ADME/neuro PK characterization and Parkinson's disease (PD) .

• Smiles:

  FC1=C(C=2C3=C(N=CN=C3NC2)N4CCOCC4)C=CC=C1C#N

• Molecular Formula:

  C17H14FN5O

• Molecular Weight:

  323.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1527474-15-2