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Azaphilone-9

CAT: 0931-T72920-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72920-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1448460-87-4
Target
Others, HuR
Related Pathways
Others, Chromatin/Epigenetic
Bioactivity
Azaphilone-9 (AZA-9) functions as an inhibitor of the HuR-ARE RNA interaction, with an inhibition constant (IC50) of 1.2 μM, by targeting the RNA-binding protein Hu antigen R (HuR) . As HuR-RNA interactions play a critical role in stabilizing oncogenic mRNAs within tumors, Azaphilone-9 exhibits potential in inhibiting cancer cell growth and progression.
Smiles
O=C1C=2C(=C(Br)C(=O)C1(OC(C)=O)C)C=C(/C=C/C(=C/[C@H](CC)C)/C)OC2
Molecular Formula
C21H23BrO5
Molecular Weight
435.31
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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