Niclosamide sodium

• Target :

  Antibiotic|||Others|||STAT|||Parasite

• Related Pathways :

  Microbiology/Virology|||JAK/STAT signaling|||Others|||Stem Cells

• Bioactivity :

  Niclosamide sodium (BAY2353), an orally active antihelminthic agent employed in parasitic infection research, serves as a potent STAT3 inhibitor, demonstrating an IC50 of 0.25 ?M in HeLa cells. Additionally, this compound exhibits significant biological activities against cancer and effectively inhibits DNA replication in Vero E6 cells.

• Smiles :

  O=[N+]([O-])C1=CC(Cl)=C(NC(C2=C([O-])C=CC(Cl)=C2)=O)C=C1.[Na+]

• Molecular Formula :

  C13H7Cl2N2NaO4

• Molecular Weight :

  349.1

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  40321-86-6