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Antioxidant agent-8

CAT: 0931-T72506-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72506-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Beta Amyloid
Related Pathways
Neuroscience, Others
Bioactivity
Antioxidant agent-8, an orally active compound, inhibits Aβ 1-42 deposition by preventing fibril aggregation (IC 50 = 11.15 μM) and aiding in fibril disaggregation (IC 50 = 6.87 μM) . It counteracts Cu2+-induced Aβ 1-42 fibril aggregation and disaggregation with lower IC 50 values of 3.69 μM and 3.35 μM, respectively. Additionally, it exhibits antioxidant and anti-inflammatory activities, demonstrates biosafety and blood-brain barrier permeability, and provides a neuroprotective effect.
Smiles
C1COC(=C(C1=O)O)/C=C/C2=CC(=C(C=C2)O)O
Molecular Formula
C13H12O5
Molecular Weight
248.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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