Antioxidant agent-8

CAT: 0931-MF-0146209-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0146209-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Beta Amyloid
Related Pathways
Neuroscience|||Others
Bioactivity
Antioxidant agent-8, an orally active compound, inhibits A? 1-42 deposition by preventing fibril aggregation (IC 50 = 11.15 µM) and aiding in fibril disaggregation (IC 50 = 6.87 µM) . It counteracts Cu2+-induced A? 1-42 fibril aggregation and disaggregation with lower IC 50 values of 3.69 µM and 3.35 µM, respectively. Additionally, it exhibits antioxidant and anti-inflammatory activities, demonstrates biosafety and blood-brain barrier permeability, and provides a neuroprotective effect.
Smiles
C1COC(=C(C1=O)O)/C=C/C2=CC(=C(C=C2)O)O
Molecular Formula
C13H12O5
Molecular Weight
248.23
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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