WIN 66306

CAT: 0931-MF-0145958-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0145958-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
151928-32-4
Target
Others|||Neurokinin receptor
Related Pathways
Neuroscience|||GPCR/G Protein|||Others
Bioactivity
WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated guinea pig ileum in a concentration-dependent manner.
Smiles
CC(C)[C@H](NC(=O)CNC(=O)[C@@H]1CC=CN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)C(=O)NCC(=O)N[C@H](C=O)[C@H](O)c1ccc(O)c(CC=C(C)C)c1
Molecular Formula
C41H52N8O9
Molecular Weight
800.9
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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