WIN 66306

• Target :

  Others|||Neurokinin receptor

• Related Pathways :

  Neuroscience|||GPCR/G Protein|||Others

• Bioactivity :

  WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated guinea pig ileum in a concentration-dependent manner.

• Smiles :

  CC(C)[C@H](NC(=O)CNC(=O)[C@@H]1CC=CN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)C(=O)NCC(=O)N[C@H](C=O)[C@H](O)c1ccc(O)c(CC=C(C)C)c1

• Molecular Formula :

  C41H52N8O9

• Molecular Weight :

  800.9

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  151928-32-4