APKC-I

• Target:

  Others|||PKC

• Related Pathways:

  Others|||Cytoskeletal Signaling|||Chromatin/Epigenetic

• Bioactivity:

  APKC-I is an inhibitor of atypical protein kinase C (aPKC) which inhibits both PKC? and PKC? with high specificity and prevents VEGF-induced endothelial permeability in cell culture and in vivo, thereby blocking ischemia-reperfusion (IR) -induced permeability.

• Smiles:

  CCOC (=O) C1=C (N) SC=C1C1=CC (OC) =C (OC) C=C1

• Molecular Formula:

  C15H17NO4S

• Molecular Weight:

  307.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  15854-12-3