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F5446

CAT: 0931-T71890Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T71890Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2304465-89-0
Target
Histone Methyltransferase, Apoptosis
Related Pathways
Apoptosis, Chromatin/Epigenetic
Purity
0.9856
Bioactivity
F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor. It promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3 on the FAS promoter to increase Fas expression, while inhibiting CTL effector gene expression.
Smiles
COC(=O)c1cc2-c3c(c[nH]c3C(=O)C(=O)c2n1S(=O)(=O)c1ccc(Cl)cc1)C(=O)OCc1ccccc1
Molecular Formula
C26H17ClN2O8S
Molecular Weight
552.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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BA4832-5.1F5446
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