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DNJNAc

CAT: 0931-T71525-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T71525-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
105265-96-1
Target
Hexokinase, glycosidase
Related Pathways
Metabolism
Purity
0.9937
Bioactivity
DNJNAc, also known as 2-Acetamido-1,2-dideoxynojirimycin, is a highly potent and specific inhibitor of β-hexosaminidase (HEX) . HEX enzymes catalyze the hydrolysis of terminal non-reducing N-acetyl-β-D-glucosamine (GlcNAc) and N-acetyl-β-D-galactosamine (GalNAc) residues from glycoconjugates such as glycoproteins, gangliosides, and glycosaminoglycans. HEX secreted by chondrocytes into the extracellular space contributes to cartilage matrix degradation, and HEX activity is elevated in the synovial fluid of osteoarthritis patients.
Smiles
N(C(C)=O)[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)NC1
Molecular Formula
C8H16N2O4
Molecular Weight
204.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-114559-01DNJNAc

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