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Metaxalone-d6

CAT: 0931-T71285Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T71285Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1189944-95-3
Target
NF-κB
Related Pathways
NF-κB, Metabolism
Bioactivity
Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 μM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone have been used in the treatment of lower back pain.
Smiles
C(OC1=CC(C([2H])([2H])[2H])=CC(C([2H])([2H])[2H])=C1)C2OC(=O)NC2
Molecular Formula
C12H9D6NO3
Molecular Weight
227.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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