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Omadacycline HCl

CAT: 0931-T71266-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T71266-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1196800-39-1
Target
Antibacterial, Antibiotic, Others
Related Pathways
Microbiology/Virology, Others
Bioactivity
Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection) . The primary effect of omadacycline is on bacterial protein synthesis, inhibiting protein synthesis with a potency greater than that of tetracycline. The binding site for omadacycline is similar to that for tetracycline.
Smiles
Cl.[H][C@@]12Cc3c(cc(CNCC(C)(C)C)c(O)c3C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2)N(C)C
Molecular Formula
C29H41ClN4O7
Molecular Weight
593.118
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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