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LY2780301

CAT: 0931-T71188-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T71188-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1226801-23-5
Target
Akt, Others
Related Pathways
Others, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Bioactivity
LY2780301 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor LY2780301 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway, thereby leading to inhibition of cell proliferation and the induction of apoptosis in tumor cells. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents.
Smiles
C(CN(C)C)N1C(=NC(=C1)C2=CC(C(F)(F)F)=C(F)C=C2)C3CCN(CC3)C4=C5C(NC(=O)C5)=NC=N4
Molecular Formula
C25H27F4N7O
Molecular Weight
517.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
E1710-01LY2780301

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