Ambroxol-d5

• Target :

  Autophagy|||glycosidase

• Related Pathways :

  Metabolism|||Autophagy

• Bioactivity :

  Ambroxol-d5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol decreases IL-13-induced production of mucin 5AC (MUC5AC) in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous particles in the same cells. Ambroxol increases phenol red secretion, a marker of expectorant activity, in mice when administered at doses of 30, 60, or 120 mg/kg. Formulations containing ambroxol have been used in the treatment of acute or chronic respiratory conditions.

• Smiles :

  C(N[C@H]1CC([C@](O)(C(C1)([2H])[2H])[2H])([2H])[2H])C2=C(N)C(Br)=CC(Br)=C2

• Molecular Formula :

  C13H13Br2D5N2O

• Molecular Weight :

  383.13

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1246818-80-3