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Tebuconazole-d9

CAT: 0931-T71142-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T71142-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1246818-83-6
Target
Antifungal, Cytochromes P450
Related Pathways
Metabolism, Microbiology/Virology
Bioactivity
Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 μM) and is cytotoxic (EC20 = 38.9 μM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per day) administered during gestation reduces testosterone levels and increases testicular levels of progesterone and 17α-hydroxyprogesterone in male rat fetuses. It has a feminizing effect on male pups and a virializing effect on female pups. When administered to rats gestationally through postnatal day 42, tebuconazole (20 and 60 mg/kg per day) leads to cell death of pyramidal cells in the CA3-4 region of the hippocampus and layer V of the cortex concomitant with impairment in learning......
Smiles
C(CN1C=NC=N1)(CCC2=CC=C(Cl)C=C2)(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])O
Molecular Formula
C16H13ClD9N3O
Molecular Weight
316.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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