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Albendazole-d7

CAT: 0931-T71055-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0931-T71055-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1287076-43-0
Target
Parasite, Antibiotic
Related Pathways
Microbiology/Virology
Bioactivity
Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Albendazole (0.05% in the diet) protects mice against lethal infection with A. suum larvae. It also inhibits growth of HT-29 human colorectal cancer cells (IC50 = 0.12 μM), halts the cell cycle at the G2/M phase, and induces apoptosis. In an HT-29 mouse xenograft model, it inhibits peritoneal tumor growth when administered intraperitoneally at a dose of 150 mg/kg but not when administered orally. Albendazole inhibits mammalian tubulin polymerization and inhibits binding of [3H]mebendazole t......
Smiles
N(C(OC)=O)C=1NC=2C(N1)=CC(SC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H])=CC2
Molecular Formula
C12H8D7N3O2S
Molecular Weight
272.38
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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