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JMN13497

CAT: 0931-T70977-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70977-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1320213-49-7
Target
Others
Related Pathways
Others
Bioactivity
JMN13497 is an precursor compound to for synthesis of scytonemin. Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin , representing a novel Plk1 inhibitor, induced the inhibition of cell growth and cell cycle arrest in multiple myeloma cells by specifically decreasing Plk1 activity. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming) .
Smiles
O=C\1C(C2=C(/C1=C\C3=CC=C(OC)C=C3)NC=4C2=CC=CC4)C5C6=C(/C(=C\C7=CC=C(OC)C=C7)/C5=O)NC=8C6=CC=CC8
Molecular Formula
C38H28N2O4
Molecular Weight
576.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5813518JMN13497

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