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Banoxantrone

CAT: 0931-T70860-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T70860-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
136470-65-0
Target
Others, NO Synthase
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. This compound demonstrates significant cytotoxicity with its hypoxia-selective action being augmented by radiation.
Smiles
N(CCN(C)(C)=O)C1=C2C(=C(NCCN(C)(C)=O)C=C1)C(=O)C=3C(C2=O)=C(O)C=CC3O
Molecular Formula
C22H28N4O6
Molecular Weight
444.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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