Banoxantrone

• Target :

  Others|||NO Synthase

• Related Pathways :

  Others|||Immunology/Inflammation

• Bioactivity :

  Banoxantrone (AQ4N), a hypoxia-selective cytotoxin prototype, undergoes reduction to AQ4, effectively inhibiting topoisomerase II. It selectively targets and eradicates hypoxic cells through an iNOS-dependent mechanism. This compound demonstrates significant cytotoxicity with its hypoxia-selective action being augmented by radiation.

• Smiles :

  N(CCN(C)(C)=O)C1=C2C(=C(NCCN(C)(C)=O)C=C1)C(=O)C=3C(C2=O)=C(O)C=CC3O

• Molecular Formula :

  C22H28N4O6

• Molecular Weight :

  444.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  136470-65-0