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Deleobuvir sodium

CAT: 0931-T70846-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70846-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1370023-80-5
Target
Others, Endogenous Metabolite
Related Pathways
Others, Metabolism
Bioactivity
Deleobuvir sodium is the salt form of Deleobuvir, also known as BI207127, a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C. Deleobuvir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including faldaprevir. Deleobuvir showed that a triple combination of deleobuvir, faldaprevir, and ribavirin performed well in HCV genotype 1b patients. Efficacy fell below 50%, however, for dual regimens without ribavirin and for genotype 1a patients. In December 2013, deleobuvir was discontinued since recent findings from phase III trials did not suggest sufficient efficacy.
Smiles
[Na+].Cn1c(c(C2CCCC2)c2ccc(cc12)C(=O)NC1(CCC1)c1nc2ccc(\C=C\C([O-])=O)cc2n1C)-c1ncc(Br)cn1
Molecular Formula
C34H32BrN6NaO3
Molecular Weight
675.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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