PF-03671148

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring.

• Smiles:

  CC1=NC (N2C (=CC=N2) C=3C=C4C (=CC3) N=CN (C) C4=O) =CC=C1

• Molecular Formula:

  C18H15N5O

• Molecular Weight:

  317.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1378524-25-4