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PF-03671148

CAT: 0931-T70826-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70826-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1378524-25-4
Target
Others
Related Pathways
Others
Bioactivity
PF-03671148 is a potent ALK inhibitor. PF-03671148 inhibits the expression of fibrotic genes and protein markers both in vitro in human fibroblasts and in vivo in a rat wound repair model. Wound healing is not inhibited by the topical application of the ALK5 inhibitor to the wound. PF-03671148 may have potential utility for the prevention of dermal scarring.
Smiles
CC1=NC(N2C(=CC=N2)C=3C=C4C(=CC3)N=CN(C)C4=O)=CC=C1
Molecular Formula
C18H15N5O
Molecular Weight
317.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C