Bupranolol HCl

CAT: 0931-T70506-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T70506-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

15148-80-8

Target

Adrenergic Receptor, Others

Related Pathways

Neuroscience, Others, GPCR/G Protein

Bioactivity

Bupranolol is a non-selective beta blocker without intrinsic sympathomimetic activity (ISA), but with strong membrane stabilizing activity. Its potency is similar to propranolol. Bupranolol is quickly and completely absorbed from the gut. Over 90% undergo first-pass metabolism. Bupranolol has a plasma half life of about two to four hours, with levels never reaching 1 μg/l in therapeutic doses. The main metabolite is carboxybupranolol, 4-chloro-3-[3- (1,1-dimethylethylamino) -2-hydroxy-propyloxy]benzoic acid – that is, the methyl group at the benzene ring is oxidized to a carboxyl group –, of which 88% are eliminated renally within 24 hours.

Smiles

Cl.Cc1ccc(Cl)c(OCC(O)CNC(C)(C)C)c1

Molecular Formula

C14H23Cl2NO2

Molecular Weight

308.243

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Bupranolol HCl

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