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XK469

CAT: 0931-T70430-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70430-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
157435-10-4
Target
Others
Related Pathways
Others
Bioactivity
XK489 is a synthetic quinoxaline phenoxypropionic acid derivative with proapoptotic and antiproliferative activities. R (+) XK469 selectively inhibits topoisomerase II-beta, blocks activation of MEK/MAPK signaling kinases, stimulates caspases, and upregulates p53-dependent proteins, including cyclins A and B1, thereby arresting cancer cells in the G2/M phase of the cell cycle. Both R (+) and S (-) isomers of this agent are cytotoxic, although the R-isomer is more potent.
Smiles
O(C1=NC2=C(N=C1)C=CC(Cl)=C2)C3=CC=C(OC(C(O)=O)C)C=C3
Molecular Formula
C17H13ClN2O4
Molecular Weight
344.75
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
HY-120679XK469

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