TLN-232

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.

• Smiles :

  C(C=1C=2C(NC1)=CC=CC2)[C@@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N[C@@H]([C@@H](C)O)C(N)=O)=O)CSSC[C@H](NC([C@@H](CC4=CC=CC=C4)N)=O)C(=O)N3

• Molecular Formula :

  C36H49N9O7S2

• Molecular Weight :

  783.96

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  158899-10-6