TLN-232

CAT: 0931-MF-0144807-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0144807-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
158899-10-6
Target
Others
Related Pathways
Others
Bioactivity
TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells.
Smiles
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N[C@@H]([C@@H](C)O)C(N)=O)=O)CSSC[C@H](NC([C@@H](CC4=CC=CC=C4)N)=O)C(=O)N3
Molecular Formula
C36H49N9O7S2
Molecular Weight
783.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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