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Cangrelor free acid

CAT: 0931-T70335-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70335-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
163706-06-7
Target
P2Y Receptor, Others
Related Pathways
Neuroscience, GPCR/G Protein, Others
Bioactivity
Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. It does not require metabolic conversion to an active metabolite. This allows cangrelor's immediate effect after infusion, and the therapeutic effects can be maintained with continuous infusion.
Smiles
N(CCSC)C1=C2C(N(C=N2)[C@@H]3O[C@H](COP(OP(C(P(=O)(O)O)(Cl)Cl)(=O)O)(=O)O)[C@@H](O)[C@H]3O)=NC(SCCC(F)(F)F)=N1
Molecular Formula
C17H25Cl2F3N5O12P3S2
Molecular Weight
776.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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