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AZ1366

CAT: 0931-T70312-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70312-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1645286-58-3
Target
Others
Related Pathways
Others
Bioactivity
AZ1366 is a potent tankyrase inhibitor that enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance. Combination AZ1366 and irinotecan achieved greater anti-tumor effects compared to monotherapy. Activity was limited to CRC explants that displayed irinotecan resistance and increased protein levels of tankyrase and NuMA.
Smiles
C(O)C1=C2C(C(=O)N=C(N2)C3=CC=C(C=C3)C=4C(C)=CC(NCCOC)=NC4)=CC=C1
Molecular Formula
C24H24N4O3
Molecular Weight
416.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5812853AZ1366

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