Products for Research Use Only

PLX7683

CAT: 0931-T70308-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T70308-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1652573-86-8
Target
Others
Related Pathways
Others
Bioactivity
PLX7683 is a paradox breaker. Paradox breakers overcame several known mechanisms of resistance to first-generation RAF inhibitors. Dissociating MAPK pathway inhibition from paradoxical activation might yield both improved safety and more durable efficacy than first-generation RAF inhibitors
Smiles
CCN(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F
Molecular Formula
C23H19ClF2N4O3S
Molecular Weight
504.94
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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