Roridin E

• Target :

  Antibiotic|||Others|||Antifungal

• Related Pathways :

  Others|||Microbiology/Virology

• Bioactivity :

  Roridin E inhibits the receptor tyrosine kinases FGFR3, IGF-1R, PDGFR?, and TrkB (IC50s = 0.4, 0.4, 1.4, and 1 ?M, respectively) and induces cytotoxicity in multiple breast cancer cell lines (IC50s = 0.02-0.05 nM) . It also inhibits proliferation in a panel of additional cancer cell lines (IC50s = <0.01 ?M) .

• Smiles :

  CC(O)C1OCC\C(C)=C\C(=O)OCC23CCC(C)=CC2OC2CC(OC(=O)\C=C/C=C/1)C3(C)C21CO1

• Molecular Formula :

  C29H38O8

• Molecular Weight :

  514.61

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  16891-85-3