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Roridin E

CAT: 931-T70276-01Size: 500 µgDry Ice: NoHazardous: No
500 µgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
16891-85-3
Target
Antibiotic|||Others|||Antifungal
Related Pathways
Others|||Microbiology/Virology
Bioactivity
Roridin E inhibits the receptor tyrosine kinases FGFR3, IGF-1R, PDGFR?, and TrkB (IC50s = 0.4, 0.4, 1.4, and 1 ?M, respectively) and induces cytotoxicity in multiple breast cancer cell lines (IC50s = 0.02-0.05 nM) . It also inhibits proliferation in a panel of additional cancer cell lines (IC50s = <0.01 ?M) .
Smiles
CC(O)C1OCC\C(C)=C\C(=O)OCC23CCC(C)=CC2OC2CC(OC(=O)\C=C/C=C/1)C3(C)C21CO1
Molecular Formula
C29H38O8
Molecular Weight
514.61
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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