PAT-347

CAT: 0931-MF-0144693-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0144693-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1689554-51-5
Target
Others|||PDE
Related Pathways
Metabolism|||Others
Bioactivity
PAT-347 is a potent Autotaxin Inhibitor. Autotaxin (ATX) is a secreted enzyme responsible for the hydrolysis of lysophosphatidylcholine (LPC) to the bioactive lysophosphatidic acid (LPA) and choline. The ATX-LPA signaling pathway is implicated in cell survival, migration, and proliferation; thus, the inhibition of ATX is a recognized therapeutic target for a number of diseases including fibrotic diseases, cancer, and inflammation, among others.
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C(CN1C=2C(C(SC3=C(F)C(C(O)=O)=CC=C3)=C1C)=CC=C(Cl)C2F)(=O)N4CC5(C=6C4=CC=CC6)CC5
Molecular Formula
C28H21ClF2N2O3S
Molecular Weight
538.99
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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