PAT-347

CAT: 0931-T70275-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T70275-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1689554-51-5

Target

Others, PDE

Related Pathways

Metabolism, Others

Bioactivity

PAT-347 is a potent Autotaxin Inhibitor. Autotaxin (ATX) is a secreted enzyme responsible for the hydrolysis of lysophosphatidylcholine (LPC) to the bioactive lysophosphatidic acid (LPA) and choline. The ATX-LPA signaling pathway is implicated in cell survival, migration, and proliferation; thus, the inhibition of ATX is a recognized therapeutic target for a number of diseases including fibrotic diseases, cancer, and inflammation, among others.

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C(CN1C=2C(C(SC3=C(F)C(C(O)=O)=CC=C3)=C1C)=CC=C(Cl)C2F)(=O)N4CC5(C=6C4=CC=CC6)CC5

Molecular Formula

C28H21ClF2N2O3S

Molecular Weight

538.99

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T87111-01	PAT-IN-2
T9901A-1103-01	PAT-LM1
T12372	PAT-505
T73530-01	2-PAT

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GTR19209711-01	PAT-347
MBS5777990	PAT-347 sodium
571507-01	Pat
BA9123-5.1	TED-347
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PAT-347

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