LYRM03

CAT: 0931-T70145-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T70145-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1820750-36-4

Target

Others

Related Pathways

Others

Bioactivity

LYRM03 is an aminopeptidase inhibitor. LYRM03 is also an ubenimex derivative. LYRM03 attenuates LPS-induced acute lung injury in mice by suppressing the TLR4 signaling pathway. LYRM03 effectively attenuates LPS-induced ALI by inhibiting the expression of pro-inflammatory mediators and Myd88-dependent TLR4 signaling pathways in alveolar macrophages. LYRM03 may serve as a potential treatment for sepsis-mediated lung injuries.

Smiles

[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)(NC([C@H]([C@@H](CC1=CC=CC=C1)N)O)=O)C(C)C

Molecular Formula

C21H33N3O5

Molecular Weight

407.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C