Bomedemstat ditosylate

• Target:

  Apoptosis|||Histone Demethylase

• Related Pathways:

  Apoptosis|||Chromatin/Epigenetic

• Purity:

  0.9905

• Bioactivity:

  Bomedemstat ditosylate (IMG-7289 ditosylate) is an orally active lysine-specific demethylase 1 (LSD1) inhibitor with antitumor activity that potentiates the response to PD-1 inhibition in a homozygous model of SCLC, inhibits cancer cell proliferation, and induces apoptosis. Bomedemstat ditosylate can be used to study myeloproliferative neoplasms and myelofibrosis.

• Smiles:

  Cc1ccc (cc1) S (O) (=O) =O.Cc1ccc (cc1) S (O) (=O) =O.[H][C@]1 (C[C@H]1NCCC[C@H] (NC (=O) c1ccc (cc1) -n1ccnn1) C (=O) N1CCN (C) CC1) c1ccc (F) cc1

• Molecular Formula:

  C42H50FN7O8S2

• Molecular Weight:

  864.02

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1990504-72-7