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JPI-547 HCl

CAT: 0931-T69955-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69955-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2055357-65-6
Target
Others
Related Pathways
Others
Bioactivity
JPI 547, also known as NOV 1402, is an oral inhibitor of PARP 1/2 and Tankyrase 1/2. JPI-547 demonstrated anti-tumor activity in BRCA-deficient xenograft models as a single-agent and in combination with chemotherapy and immune checkpoint inhibitors.
Smiles
Cl.Cl.O=c1[nH]c2cc(CN3CCN(CC3)c3ccc(cn3)C#N)ccc2c2NCCCc12
Molecular Formula
C23H26Cl2N6O
Molecular Weight
473.402
Shipping Conditions
Ice Packs
Storage Temperature
-20°C