Products for Research Use Only
RegisterLogin

Lonaprisan

CAT: 0931-T69895-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T69895-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
211254-73-8
Target
Others, Progesterone Receptor
Related Pathways
Others
Bioactivity
Lonaprisan is an orally bioavailable pentafluoroethyl derivative of a mifepristone-related steroid with antiprogestagenic activity. Lonaprisan is a pure, highly receptor-selective progesterone receptor (PR) antagonist; binding of this agent to PRs inhibits PR activation and the associated proliferative effects. Unlike many other antiprogestins such as mifepristone, this agent does not appear to convert to an agonist in the presence of protein kinase A (PKA) activators and shows high antiprogestagenic activity on both progesterone receptor (PR) isoforms PR-A and PR-B.
Smiles
C[C@@]12[C@]([C@]3(C([C@H](C1)C4=CC=C(C(C)=O)C=C4)=C5C(CC3)=CC(=O)CC5)[H])(CC[C@]2(C(C(F)(F)F)(F)F)O)[H]
Molecular Formula
C28H29F5O3
Molecular Weight
508.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
MBS5812439Lonaprisan
A14130-100Lonaprisan 100mg
A14130-10Lonaprisan 10mg
A14130-50Lonaprisan 50mg
A14130-25Lonaprisan 25mg
A14130-5Lonaprisan 5mg

Popular Products